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NCBI, GenBank and EBI

NCBI(National Center for Biotechnology Information):
As a national resource for molecular biology information, NCBI's mission is to develop new information technologies to aid in the understanding of fundamental molecular and genetic processes that control health and disease. More specifically, the NCBI has been charged with creating automated systems for storing and analyzing knowledge about molecular biology, biochemistry, and genetics; facilitating the use of such databases and software by the research and medical community; coordinating efforts to gather biotechnology information both nationally and internationally; and performing research into advanced methods of computer-based information processing for analyzing the structure and function of biologically important molecules.
To carry out its diverse responsibilities, NCBI:
• Conducts research on fundamental biomedical problems at the molecular level using mathematical and computational methods
• Maintains collaborations with several NIH institutes, academia, industry, and other governmental agencies
• Fosters scientific communication by sponsoring meetings, workshops, and lecture series
• Supports training on basic and applied research in computational biology for postdoctoral fellows through the NIH Intramural Research Program
• Engages members of the international scientific community in informatics research and training through the Scientific Visitors Program
• Develops, distributes, supports, and coordinates access to a variety of databases and software for the scientific and medical communities
• Develops and promotes standards for databases, data deposition and exchange, and biological nomenclature.

GenBank is genetic sequence database, an annotated collection of all publicly available DNA sequences. A new release is made every two months. GenBank is part of the International Nucleotide Sequence Database Collaboration, which is comprised of the DNA Data Bank of Japan (DDBJ), the European Molecular Biology Laboratory (EMBL), and GenBank at the National Center for Biotechnology Information. These three organizations exchange data on a daily basis.Each GenBank entry includes a concise description of the sequence, the scientific name and taxonomy of the source organism, and a table of features that identifies coding regions and other sites of biological significance, such as transcription units, sites of mutations or modifications, and repeats. Protein translations for coding regions are included in the feature table. Bibliographic references are included along with a link to the Medline unique identifier for all published sequences.

The European Bioinformatics Institute (EBI) is a non-profit academic organisation that forms part of the European Molecular Biology Laboratory (EMBL).
The EBI is a centre for research and services in bioinformatics. The Institute manages databases of biological data including nucleic acid, protein sequences and macromolecular structures.


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